In TOOsonix we are constantly working with clinical and other academia partners to expand our knowledge and expertise. We are committed to publish results that can assist our own company as well as our customers and partners to follow our mission:
Create better lives with high frequency ultrasound therapy.
We will continuously be adding publications as they are published and become publicly available.
We strive to make information and clinical papers available through Open Access, but some papers are only available through registered libraries.
Please contact us directly for copies of these if you do not have the appropriate licenses.
JEADV Clin Pract. 2024; 1–7
Protocol for high-intensity focused ultrasound (HIFU) treatment of cutaneous neurofibromas.
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Note: Please visit Journal site to download supplemental video.
Front Oncol. 2024 Jul 18:14:1428702. 1–7.
Case report: Sequential treatment strategy for advanced basal cell carcinoma in Gorlin-Goltz syndrome: Integration of Vismodegib, radiotherapy, surgery, and high-intensity focused ultrasound.
Calik J, lizlo M O, Slocka-Romaniuk B, Elsaftawy A, Sauer N.
Case Rep Dermatol. 2024; 16 (1): 164–172
Recalcitrant Basal Cell Carcinoma after Grenz Ray Therapy: Introduction of High-Intensity Focused Ultrasound for Minimally Invasive Management
Serup J, Zawada T, Bove T.
J. Clin. Med. 2024; 13(11); 3277: 1-45
Pilot Study on High-Intensity Focused Ultrasound (HIFU) for Basal Cell Carcinoma: Effectiveness and Safety
Calik J, Sauer N, Wozniak B, Wojnar A, Pietkiewicz P, Dziegiel P.
Dermatol Ther. 2024 May; 14(5): 1189-1210
High Intensity Focused Ultrasound (20 MHz) and Cryotherapy as Therapeutic Options for Granuloma Annulare and Other Inflammatory Skin Conditions.
Calik J, Zawada T, Sauer N, Bove T.
JEADV Clin Pract. 2024: 1049-1060
High‐intensity focused ultrasound: safety and efficacy of a novel treatment modality for neurofibromatosis type 1 cutaneous neurofibroma.
Peltonen S, Serup J, Tang M, Gillstedt M, Kantere D, Neittaanmäki N, Holmström P, Blakeley J O, Rosner K, Roberts R, Bove T, Karmisholt K E.
Applied Acoustics, 2024;221: 1-19
Analytical modeling of harmonically driven focused acoustic sources with experimental verification.
Zawada T, Bove T.
Journal of Clinical Medicine. 2024;13(4); 931: 1-19
Healing Process after High-Intensity Focused Ultrasound Treatment of Benign Skin Lesions: Dermoscopic Analysis and Treatment Guidelines.
Calik J, Zawada T, Bove T, Dzięgiel P, Pogorzelska-Antkowiak A, Mackiewicz J, Woźniak B, Sauer N.
IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Jan;71(1): 16-26
Head-to-Head Comparison of Acoustic Properties of Lead-Free and PZT-Based HIFU Transducers Operating at 12 MHz.
Zawada T, Bove T, Lou-Moller R, Ringgaard E.
Case Rep Dermatol 2023;15(1): 194–201
Treatment of Cutaneous Neurofibromas in Patients with Neurofibromatosis Type 1.
Wozniak B, Bove T, Zawada T, Calik J.
Ultrasound Med Biol. 2022 Dec;48(12): 2530-2543
Lead-Free HIFU Transducers.
Zawada T, Bove T, Astafiev K, Ringgaard E, Lou-Moeller R.
Curr Probl Dermatol. 2022;56: 268-280
High-Frequency (20 MHz) Focused Ultrasound: A Novel Method for Noninvasive Tattoo Removal.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
2022 IEEE International Ultrasonics Symposium (IUS), Venice, Italy, 2022: 1-4
Acoustic field of strongly focused HIFU transducer operating at 20 MHz – comparison of public domain numerical simulators with experimental observations.
Zawada T, Bove T,
Case Rep Dermatol. 2022: 275-282
Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream.
Calik J, Zawada T, Bove T
Ultrasound in Medicine & Biology. 2022;48(7): 1309–1327
Strongly Focused HIFU Transducers With Simultaneous Optical Observation for Treatment of Skin at 20 MHz.
Zawada T, Bove T.
Clin Cosmet Investig Dermatol. 2022;15: 145-156
Treatment of seborrheic keratosis by high frequency focused ultrasound: an early experience with 11 consecutive cases.
Calik J, Migdal M, Zawada T, Bove T.
Dermatology. 2022; 238(4): 662–667
Efficacy assessment of the high-frequency high-intensity focused ultrasound as a new treatment for actinic keratosis.
Jafari S M S, Cazzaniga S, Bossart S, Feldmeyer L, Pelloni L, Rhyn M v, Angermeier S, Adatto M, Hunger R E, Heidemeyer K.
J Cosmet Dermatol. 2022;21: 3371–3379
Treatment of superficial benign vascular tumors by high intensity focused ultrasound: observations in two illustrative cases.
Calik J, Zawada T, Bove T.
Case Rep Dermatol. 2021;13(2): 340–346
Removal of common warts by high-intensity focused ultrasound: an introductory observation.
Bove T, Zawada T, Jessen A, Poli M, Serup J.
Skin Res Technol. 2020;26: 824–831
High-frequency (20 MHz) high-intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol 2020;26: 839–850
High-frequency (20 MHz) high-intensity focused ultrasound: New ablative method for color-independent tattoo removal in 1-3 sessions: An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M
Skin Res Technol 2020;26: 241–254
High-frequency (20 MHz) high-intensity focused ultrasound system for dermal intervention: A 12-week local tolerance study in minipigs.
Soegaard S, Aarup V, Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol. 2019;25: 217–228
High-frequency (20-MHz) high-intensity focused ultrasound (HIFU) system for dermal intervention: Preclinical evaluation in skin equivalents.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
Front Oncol. 2024 Jul 18:14:1428702. 1–7.
Case report: Sequential treatment strategy for advanced basal cell carcinoma in Gorlin-Goltz syndrome: Integration of Vismodegib, radiotherapy, surgery, and high-intensity focused ultrasound.
Calik J, lizlo M O, Slocka-Romaniuk B, Elsaftawy A, Sauer N.
Case Rep Dermatol. 2024; 16 (1): 164–172
Recalcitrant Basal Cell Carcinoma after Grenz Ray Therapy: Introduction of High-Intensity Focused Ultrasound for Minimally Invasive Management
Serup J, Zawada T, Bove T.
J. Clin. Med. 2024; 13(11); 3277: 1-45
Pilot Study on High-Intensity Focused Ultrasound (HIFU) for Basal Cell Carcinoma: Effectiveness and Safety
Calik J, Sauer N, Wozniak B, Wojnar A, Pietkiewicz P, Dziegiel P.
Dermatol Ther. 2024 May; 14(5): 1189-1210
High Intensity Focused Ultrasound (20 MHz) and Cryotherapy as Therapeutic Options for Granuloma Annulare and Other Inflammatory Skin Conditions.
Calik J, Zawada T, Sauer N, Bove T.
JEADV Clin Pract. 2024: 1–12
High‐intensity focused ultrasound: safety and efficacy of a novel treatment modality for neurofibromatosis type 1 cutaneous neurofibroma.
Peltonen S, Serup J, Tang M, Gillstedt M, Kantere D, Neittaanmäki N, Holmström P, Blakeley J O, Rosner K, Roberts R, Bove T, Karmisholt K E.
Applied Acoustics, 2024;221: 1-19
Analytical modeling of harmonically driven focused acoustic sources with experimental verification.
Zawada T, Bove T.
Journal of Clinical Medicine. 2024;13(4); 931: 1-19
Healing Process after High-Intensity Focused Ultrasound Treatment of Benign Skin Lesions: Dermoscopic Analysis and Treatment Guidelines.
Calik J, Zawada T, Bove T, Dzięgiel P, Pogorzelska-Antkowiak A, Mackiewicz J, Woźniak B, Sauer N.
IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Jan;71(1): 16-26
Head-to-Head Comparison of Acoustic Properties of Lead-Free and PZT-Based HIFU Transducers Operating at 12 MHz.
Zawada T, Bove T, Lou-Moller R, Ringgaard E.
Case Rep Dermatol 2023;15(1): 194–201
Treatment of Cutaneous Neurofibromas in Patients with Neurofibromatosis Type 1.
Wozniak B, Bove T, Zawada T, Calik J.
Ultrasound Med Biol. 2022 Dec;48(12): 2530-2543
Lead-Free HIFU Transducers.
Zawada T, Bove T, Astafiev K, Ringgaard E, Lou-Moeller R.
Curr Probl Dermatol. 2022;56: 268-280
High-Frequency (20 MHz) Focused Ultrasound: A Novel Method for Noninvasive Tattoo Removal.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
2022 IEEE International Ultrasonics Symposium (IUS), Venice, Italy, 2022: 1-4
Acoustic field of strongly focused HIFU transducer operating at 20 MHz – comparison of public domain numerical simulators with experimental observations.
Zawada T, Bove T,
Case Rep Dermatol. 2022: 275-282
Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream.
Calik J, Zawada T, Bove T
Ultrasound in Medicine & Biology. 2022;48(7): 1309–1327
Strongly Focused HIFU Transducers With Simultaneous Optical Observation for Treatment of Skin at 20 MHz.
Zawada T, Bove T.
Clin Cosmet Investig Dermatol. 2022;15: 145-156
Treatment of seborrheic keratosis by high frequency focused ultrasound: an early experience with 11 consecutive cases.
Calik J, Migdal M, Zawada T, Bove T.
Dermatology. 2022; 238(4): 662–667
Efficacy assessment of the high-frequency high-intensity focused ultrasound as a new treatment for actinic keratosis.
Jafari S M S, Cazzaniga S, Bossart S, Feldmeyer L, Pelloni L, Rhyn M v, Angermeier S, Adatto M, Hunger R E, Heidemeyer K.
J Cosmet Dermatol. 2022;21: 3371–3379
Treatment of superficial benign vascular tumors by high intensity focused ultrasound: observations in two illustrative cases.
Calik J, Zawada T, Bove T.
Case Rep Dermatol. 2021;13(2): 340–346
Removal of common warts by high-intensity focused ultrasound: an introductory observation.
Bove T, Zawada T, Jessen A, Poli M, Serup J.
Skin Res Technol. 2020;26: 824–831
High-frequency (20 MHz) high-intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol 2020;26: 839–850
High-frequency (20 MHz) high-intensity focused ultrasound: New ablative method for color-independent tattoo removal in 1-3 sessions: An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M
Skin Res Technol 2020;26: 241–254
High-frequency (20 MHz) high-intensity focused ultrasound system for dermal intervention: A 12-week local tolerance study in minipigs.
Soegaard S, Aarup V, Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol. 2019;25: 217–228
High-frequency (20-MHz) high-intensity focused ultrasound (HIFU) system for dermal intervention: Preclinical evaluation in skin equivalents.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
Front Oncol. 2024 Jul 18:14:1428702. 1–7.
Case report: Sequential treatment strategy for advanced basal cell carcinoma in Gorlin-Goltz syndrome: Integration of Vismodegib, radiotherapy, surgery, and high-intensity focused ultrasound.
Calik J, lizlo M O, Slocka-Romaniuk B, Elsaftawy A, Sauer N.
Case Rep Dermatol. 2024; 16 (1): 164–172
Recalcitrant Basal Cell Carcinoma after Grenz Ray Therapy: Introduction of High-Intensity Focused Ultrasound for Minimally Invasive Management
Serup J, Zawada T, Bove T.
J. Clin. Med. 2024; 13(11); 3277: 1-45
Pilot Study on High-Intensity Focused Ultrasound (HIFU) for Basal Cell Carcinoma: Effectiveness and Safety
Calik J, Sauer N, Wozniak B, Wojnar A, Pietkiewicz P, Dziegiel P.
Dermatol Ther. 2024 May; 14(5): 1189-1210
High Intensity Focused Ultrasound (20 MHz) and Cryotherapy as Therapeutic Options for Granuloma Annulare and Other Inflammatory Skin Conditions.
Calik J, Zawada T, Sauer N, Bove T.
JEADV Clin Pract. 2024: 1–12
High‐intensity focused ultrasound: safety and efficacy of a novel treatment modality for neurofibromatosis type 1 cutaneous neurofibroma.
Peltonen S, Serup J, Tang M, Gillstedt M, Kantere D, Neittaanmäki N, Holmström P, Blakeley J O, Rosner K, Roberts R, Bove T, Karmisholt K E.
Applied Acoustics, 2024;221: 1-19
Analytical modeling of harmonically driven focused acoustic sources with experimental verification.
Zawada T, Bove T.
Journal of Clinical Medicine. 2024;13(4); 931: 1-19
Healing Process after High-Intensity Focused Ultrasound Treatment of Benign Skin Lesions: Dermoscopic Analysis and Treatment Guidelines.
Calik J, Zawada T, Bove T, Dzięgiel P, Pogorzelska-Antkowiak A, Mackiewicz J, Woźniak B, Sauer N.
IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Jan;71(1): 16-26
Head-to-Head Comparison of Acoustic Properties of Lead-Free and PZT-Based HIFU Transducers Operating at 12 MHz.
Zawada T, Bove T, Lou-Moller R, Ringgaard E.
Case Rep Dermatol 2023;15(1): 194–201
Treatment of Cutaneous Neurofibromas in Patients with Neurofibromatosis Type 1.
Wozniak B, Bove T, Zawada T, Calik J.
Ultrasound Med Biol. 2022 Dec;48(12): 2530-2543
Lead-Free HIFU Transducers.
Zawada T, Bove T, Astafiev K, Ringgaard E, Lou-Moeller R.
Curr Probl Dermatol. 2022;56: 268-280
High-Frequency (20 MHz) Focused Ultrasound: A Novel Method for Noninvasive Tattoo Removal.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
2022 IEEE International Ultrasonics Symposium (IUS), Venice, Italy, 2022: 1-4
Acoustic field of strongly focused HIFU transducer operating at 20 MHz – comparison of public domain numerical simulators with experimental observations.
Zawada T, Bove T,
Case Rep Dermatol. 2022: 275-282
Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream.
Calik J, Zawada T, Bove T
Ultrasound in Medicine & Biology. 2022;48(7): 1309–1327
Strongly Focused HIFU Transducers With Simultaneous Optical Observation for Treatment of Skin at 20 MHz.
Zawada T, Bove T.
Clin Cosmet Investig Dermatol. 2022;15: 145-156
Treatment of seborrheic keratosis by high frequency focused ultrasound: an early experience with 11 consecutive cases.
Calik J, Migdal M, Zawada T, Bove T.
Dermatology. 2022; 238(4): 662–667
Efficacy assessment of the high-frequency high-intensity focused ultrasound as a new treatment for actinic keratosis.
Jafari S M S, Cazzaniga S, Bossart S, Feldmeyer L, Pelloni L, Rhyn M v, Angermeier S, Adatto M, Hunger R E, Heidemeyer K.
J Cosmet Dermatol. 2022;21: 3371–3379
Treatment of superficial benign vascular tumors by high intensity focused ultrasound: observations in two illustrative cases.
Calik J, Zawada T, Bove T.
Case Rep Dermatol. 2021;13(2): 340–346
Removal of common warts by high-intensity focused ultrasound: an introductory observation.
Bove T, Zawada T, Jessen A, Poli M, Serup J.
Skin Res Technol. 2020;26: 824–831
High-frequency (20 MHz) high-intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol 2020;26: 839–850
High-frequency (20 MHz) high-intensity focused ultrasound: New ablative method for color-independent tattoo removal in 1-3 sessions: An open-label exploratory study.
Serup J, Bove T, Zawada T, Jessen A, Poli M
Skin Res Technol 2020;26: 241–254
High-frequency (20 MHz) high-intensity focused ultrasound system for dermal intervention: A 12-week local tolerance study in minipigs.
Soegaard S, Aarup V, Serup J, Bove T, Zawada T, Jessen A, Poli M.
Skin Res Technol. 2019;25: 217–228
High-frequency (20-MHz) high-intensity focused ultrasound (HIFU) system for dermal intervention: Preclinical evaluation in skin equivalents.
Bove T, Zawada T, Serup J, Jessen A, Poli M.
